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Additionally, as we mentioned above, many hypoglycemic drugs have been proven effective in suppressing ferroptosis, which provides novel strategies for the treatment of ferroptosis-related diseases, such as AKI[188]

Free Radical Biol Med 21:9951000 Dringen R, Pfeiffer B, Hamprecht B (1999) Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione

however, the proportion of Buffer B (the "elution" buffer) is gradually increased from 0% to 100% according to a programmed concentration change (the "gradient")

p21 can be a barrier to ferroptosis independent of p53