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[11] Tompkins, S.C., Sheldon, R.D., Rauckhorst, A.J., Noterman, M.F., Solst, S.R., Buchanan, J.L

Homocysteine Reduction : Lowers homocysteine, protecting microvasculature of the inner ear from endothelial damage and ischemia

Statistical analysis For animal studies, sample sizes ( n = 5 per group, 3 in the tirzepatide-treated group) were determined based on prior in-house experience and previous studies using similar mouse models to ensure adequate power to detect biologically relevant effects

To induce hypercholesterolemia, the other 18 rats were divided into three groups and received a fat-rich diet with 5% cholesterol (Oyetayo et al., 2020)
