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[DOI] [PMC free article] [PubMed] [Google Scholar] 65.Knutsen K.V., Brekke M., Gjelstad S., Lagerlv P
No Approved Therapeutic Claims
The demonstration that the HPGDS-specific inhibitor HQL79, which suppresses PGD 2 production 18 , could ameliorate muscle necrosis and improve muscle strength in mdx mice in a murine model of DMD 10 has led to the development of novel potent HPGDS inhibitors, such as TAS204 19 and TAS205 20
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