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The major target of an IGF-1 antagonist is the IGF-1R, which serves as the gateway for IGF-1 action (see Figure 3)

Ye T., Jiao Z., Li X., et al., Inhaled SARSCoV2 Vaccine for SingleDose Dry Powder Aerosol Immunization, Nature 624 (2023): 630638

Moreover, this approach may offer broader applications in regenerative medicine, where maintaining stem cell integrity and tissue homeostasis is crucial

The pathogenesis of PD involves several interconnected processes centered on syn aggregation, dopaminergic neurodegeneration, and neuroinflammation
