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Abstract Integrins are considered the main cell-adhesion transmembrane receptors that play multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in biochemical and mechanical signals between cells and their environment in a wide range of states in health and diseases

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Inflammation Inflammation, a natural reaction that occurs in the body in response to injurious stimuli, is the beginning of the process used by the body to restore tissue integrity and homeostasis