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The elderly population, whose antioxidative/nitrosative defense system is weakened by higher levels of ROS and nitrogen species, is especially vulnerable to the harmful effects of this virus

10.1080/00365521.2021.1922744 152 SobhaniI.BergstenE.CouffinS.AmiotA.NebbadB.BarauC.et al (2019)

Figure 4 ALA significantly inhibits the expression of signaling proteins of ER stress following CSD In order to further investigate whether ALA would exert the hepatoprotective effects through modulating the activities of endoplasmic reticulum stress (ER stress) following CSD, the expressions of signaling proteins involved in the process of ER stress (such as ATF6, IRE1, and PERK) were quantitatively examined by the immunoblotting analysis