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In this context, fatty acids, long known for their roles as energy substrates and structural components, exert significant influence on macrophage polarization and function by activating or suppressing key signaling pathways ( In addition to the classical M1 and M2 polarization spectrum, single-cell transcriptomic studies have identified a metabolically specialized subset of macrophages termed lipid-associated macrophages (LAMs)

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La pi alta concentrazione tessutale di carnitina nei muscoli scheletrici e nel miocardio