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Furthermore, the fuel released from BMAds through lipolysis is also required to maintain bone mass during cold exposure, as the genetic ablation of ATGL specifically in BMAds prevents the decrease of BMAd cell size and induces a significant reduction in trabecular bone mass after chronic cold exposure (295)

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Celsius emphasizes that consuming the drink responsibly, such as limiting intake to one or two cans per day, keeps caffeine levels below the NCAAs 15 micrograms per milliliter urine threshold