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Although hepatocytes constitute the major cell population of the liver, direct interaction of hepatocytes with leukocytes in the blood is unlikely

Chemicals and standards LCMS grade water (H 2 O) was purchased from Honeywell (Muskegon, MI, USA)

This insight can then guide the development of multifaceted strategies targeting immune organs, cells, and signaling pathways to restore immune competence, eliminate SnCs, and delay age-related dysfunction