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1 Introduction Hypothyroidism is a prevalent endocrine disorder defined by inadequate synthesis or secretion of thyroid hormones, primarily thyroxine (T 4) and triiodothyronine (T 3) (McDermott, 2020)

c-Met is overexpressed in multiple human cancers including gastric, lung, colorectal, and hepatocellular carcinoma, where aberrant HGF/c-Met signaling drives tumor growth, invasion, and metastasis

Targeted in situ self-assembly augments peptide drug conjugate cell-entry efficiency

However, in comparison to vehicle-treated mice, mice treated with GLP-1MK-801 demonstrated a slight decrease in plasma glucagon levels (Extended Data Fig