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4.7.2 TNF and the inhibitors As an anti-inflammatory mediator, TNF- is considered to play a role in vitiligo, which may promote apoptosis in melanocytes, induce B-cell activation, increase autoantibody production, and inhibit melanogenesis (90)

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Using lip balms or ointments with SPF, wearing wide-brimmed hats, and avoiding direct sun exposure during peak hours are important preventive measures

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