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MOTS-c is the better second choice when the research question is metabolic flexibility, insulin sensitivity, obesity-related mitochondrial stress, fatty-acid oxidation, exercise adaptation, or age-related metabolic decline

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As a 26-year-old graduate student at Johns Hopkins in the early 1970s, Pert identified the opiate receptor the cellular binding site for the brain's own endorphins and then spent her career at the National Institute of Mental Health mapping how neuropeptides and their receptors form a signaling network linking brain, emotion, and immunity.3,4 She published more than 250 papers on peptides and receptors

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