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Numerous antioxidants have been recently utilized for their protective effect against pro-oxidant that induce oxidative stress either by generating ROS and RNS or by inhibiting antioxidant systems
[PubMed] [Google Scholar] 119.Huang P.-Y., Leu J.-H., Chen L.-L
Another option is to use recombinant Cas9 proteins, which produce mutations at on-target sites as soon as they are introduced into cells and are promptly eliminated by cellular protease machinery, reducing off-target effects [315]
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