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Similar to IL-31, OSM induces delayed itching in mice and enhances histamine-induced pruritus by enhancing the excitability and sensitivity of the sensory neurons to pruritogens instead of directly activating them

Chilled, prepared 1 Cell Lysis Buffer (100 l) was added to the sample tube and lysis was performed on ice for 30 min, with shaking every 5 min

Apart from angiogenesis, cancer may achieve new vasculature by vessel co-option (using existing vessels), vascular mimicry (the process of forming vessels from tumor cells) and vasculogenesis (involving bone marrow-derived progenitor cells) (120)