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doi: 10.1016/j.jcin.2010.05.004

In addition to fatigue, a deficiency of B12 can lead to other symptoms like pale skin, headaches, depression, gastrointestinal problems, difficulty concentrating, decreased mental function, mouth and tongue pain or inflammation, and paresthesia in your hands and feet

Since they also generate ROS as a byproduct in this energy production process, we need to protect them from ROS attacks to regulate their function
