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The reasons are multifactorial and remain much disputed (Reference Campbell and Turner94) , but suppression of immune cells, travel, fatigue, allergies, increased anxiety, sleep disruption and poor diet could all play a role

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Interestingly, an in-depth analysis via LCMS/MS confirmed thiol peroxidase HpTpx (18 kDa, O25151) and revealed another crucial stress-response protein, chaperonin HpGroEL (60 kDa, P42383), as significantly outcompeted targets matching the gel-based results (Fig