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2023b)and reactive polysulfides (RSS) form a parallel signalling layer that intersects ROS at several levels

Nitric oxide-mediated bystander effect induced by heavy-ions in human salivary gland tumour cells

Gut microbiota, by converting curcumin into more active metabolites through its enzymatic activity, becomes the protagonist of the pharmacokinetics and pharmacodynamics of this polyphenol (Pan et al., 2019) and, therefore, takes on a fundamental role not only in the metabolism but also in its efficacy, toxicity, and bioavailability, once administrated orally to the host (Dey, 2019)

This drug is under clinical investigation