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10.1152/ajpheart.00457.2018 90 HeR.WangZ.CuiM.LiuS.WuW.ChenM.et al (2021)

Atlanta, GA: Centers for Disease Control and Prevention (US)

Importantly, a prolonged crotalphin treatment did not lead to analgesic tolerance [208]

Therefore, in the environment where MSU is present, promoting phagocytosis of MSU or MSU protein complexes by macrophages, thereby accelerating the metabolism of MSU from the site of injury is a potentially effective way to inhibit inflammation generation
