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Transwell migration assay L929 cells (1 10 5 cells per well) were seeded into the upper chamber (8 m pore size)

Loren Pickart, who pioneered much of the research, suggested that GHK-Cu levels decrease significantly with age (1), although the exact extent of this decline varies across studies

Illustratively, growth hormone is implicated in the development of schizophrenia [306], interconnected with glutamate [307,308], GABA [309], dopamine [310], serotonin [311], catecholamines, and acetylcholine [312,313,314]

doi:10.1538/expanim.19-0138 pmid:33055491 Zhang Z, Park JW, Ahn IS, Diamante G, Sivakumar N, Arneson D, Yang X, van Veen JE, Correa SM (2021) Estrogen receptor alpha in the brain mediates tamoxifen-induced changes in physiology in mice