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The release and excessive accumulation of collagen fibers caused by overactivated fibroblasts, which are marked with fibroblast activation protein (FAP), lead to pathological changes in the extracellular matrix (ECM) and persistent inflammation, resulting in a vicious cycle of cellular activity and extracellular fibrosis 3,4,5,6,7

Synovial Fluid Mitochondrial DNA Concentration Reflects the Degree of Cartilage Damage After Naturally Occurring Articular Injury

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GSHee could be an addition to the important strategy to mitigate OIRD via co-treatment with non-OR ventilatory stimulants that do not affect opioid-induced analgesia
