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Lithium Orotate and Vitamin B12: Benefits for Mood and Cognitive SupportFor some people, low-dose, supplemental lithium orotate is a game changer when combined with vitamin B12

This is exacerbated by reduced levels of serotonin and noradrenaline within the spinal cord, principally affecting the descending antinociceptive pathways [129,130]

So, if a total B12 blood test is under 148 pmol/L (200 ng/L), then this confirms deficiency and FYI they will be symptomatic at this level, albeit the forms of symptoms and severity varies

However, every drug carries some potential side effects and the same is true for cyanocobalamin also