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I had mostly heard this from people getting moderna

10.1016/S0002-9440(10)64051-5 [DOI] [PMC free article] [PubMed] [Google Scholar] 167.Jabs WJ, Theissing E, Nitschke M, Bechtel JFM, Duchrow M, Mohamed S, et al

High prevalence of proximal and distal gastroesophageal reflux disease in advanced COPD

It is the most fundamental degradation pathway because water is the very medium the peptide sits in after reconstitution
