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The relative abundance of the microspecies, in turn, is a function of pH and the microscopic protonation constants

also showed the same trend in knee symptoms and daily activity progression using the mean KOOS score in ten participants with degenerative meniscus tears without osteoarthritis according to Stoller classification after 3 months and 6 months of follow up (i.e., KOOS: 56.6 15.7 baseline, 70.2 16.8 post- 3 months, 72.7 18.5 post- 6 months, p = 0.0007)

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Especially, Ca 2+ fluxes involving the ER and mitochondria govern apoptosis [96]