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J Am Anim Hosp Assoc 2011;47:73-82

The results of this research demonstrated that supplementation of the cryopreservation medium with L-carnitine before freezing yields a considerable enhancement in post-thaw sperm parameters and reduces sperm cryodamage in both the normozoospermic and asthenozoospermic semen samples, compared to the control group

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Results showed TMAO inhibited autophagy and activated NLRP3 inflammasome, which were reversed by ATG16L1 or NLRP3 knockdown, indicating a mechanistic link in IBD pathogenesis
