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Melatonin MT1 receptors regulate the Sirt1/Nrf2/Ho-1/Gpx4 pathway to prevent alpha-synuclein-induced ferroptosis in Parkinsons disease

[DOI] [PubMed] [Google Scholar] 109.Pike FS, Berg J, King NW
Gleichzeitig untersttzt eine hhere S-Adenosylmethionin (SAM)-Verfgbarkeit wichtige methylierungsabhngige Wege, die fr epigenetische Regulation und Genexpression im Zusammenhang mit dem Energiestoffwechsel entscheidend sind

Indeed, both of these processes are mediated by toll-like receptor (TLR2 and TLR4) signaling in morphine-treated mice (Meng et al., 2013)