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Description
Covalent/irreversible inhibitors target the redox/catalytic apparatus of TGR with almost no recognition elements that give affinity and selectivity for TGR over off-targets and the cellular redox apparatus resulting in undesirable cross-reactions and low specificity in vivo 25
10.3390/ijms25179715 148

Ursodeoxycholate stimulates Na+-H+ exchange in rat liver basolateral plasma membrane vesicles

J Physiol 465: 303323
