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E-cigarettes contain several harmful compounds, including nicotine, heavy metals like nickel and lead, volatile organic compounds, and other toxins that can lead to diseases and cancers

When the mice were fed a diet deficient in choline, that is, lacking precursors required for DMG production, they failed to gain weight after smoking cessation. The second bioactive metabolite, acetylglycine, or ACG, followed a mirror-image pattern to that of DMG: Its levels were reduced during active exposure to smoke and after the exposure stopped, they increased following antibiotic treatment