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"Regulatory Impact Statement: Regulation of smokeless tobacco and nicotine-delivery products" (PDF)

Zero values were replaced using an Aitchison mean point estimate before applying the CLR transformation

Common approaches include: Microdosing: 1-5mg THC doses throughout the day for consistent relief Targeted dosing: Higher doses (10-25mg) for acute symptom flares Combination therapy: CBD-dominant products for daytime, THC-dominant for evening Multiple delivery methods: Tinctures for precise dosing, vaporizers for rapid onset The key advantage of cannabis dosing is patient autonomy and real-time adjustment capability

Available from: White V and Hayman J