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Gene expression analysis involved quantitative real-time PCR, while hormone levels were assessed via ELISA

Subgroup analysis indicated significant reduction in BMI were seen for GLP1RAs versus placebo or metformin, but not in combined treatment versus metformin monotherapy

Orforglipron 12 mg lowered HbA1c 0.48% more than semaglutide 7 mg
I totally agree where some people are always going to gain water weight, especially just from the inflammatory component
