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As sarcopenia occurs at ages as early as the 50s, ultimately leading to frailty with debility related states in the elderly, if other weight loss modalities that include calorie restriction with exercise could achieve similar CV outcomes, then that would certainly be preferable

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Gallbladder disease : Rapid weight loss may increase the risk of cholelithiasis (gallstones) and cholecystitis

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19 European medicines agency (EMA)

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Many patients may be able to restart treatment after medical evaluation, depending on their health status and treatment goals

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