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Capping more than two years of stock-gyrating drama, Pfizer said Monday that it would stop development of danuglipron, its experimental oral GLP-1 medicine to treat obesity, focusing its efforts on another medicine with a different mechanism of action

GLP-1RAs can suppress local inflammation caused by agonistic anti-CD3 antibody through intraepithelial lymphocytes (IELs) (Wong et al., 2022)

doi: 10.1210/endo.140.11.7143 15 MeierJJNauckMAKranzDHolstJJDeaconCFGaecklerDet al

After a full-text review of 39 studies, the authors included five randomized controlled clinical trials in the final analysis
