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The ketogenic diet, characterized by low carbohydrates and high fat consumption, has become increasingly popular over the last decade or so

The problem was the side effects associated, particularly with GLP-1, are what we call peak to trough: so the difference between the highest amount of drug and the lowest and then going back up again to the highest caused by this twice-a-day dosingwhich you can imagine someone bouncing around maybe two to three times, the drug at peak, then trough, causes a lot of GI distress

Need for Affordability Physicians emphasize the necessity for drastic price reductions, inclusion in public health schemes, or development of affordable biosimilars/generics for these drugs to have a real public health impact in India

and Koehler et al (58) reported exendin increased pancreatic mass in mice after one week