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After the Injection: Storage and Disposal Safety does not end when the needle comes out

[1] [2] Marketed under brand names including Ozempic, Wegovy, and Rybelsus, semaglutide works by mimicking the incretin hormone GLP-1, which enhances glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and promotes satiety through central nervous system pathways

Neuropsychopharmacol Rep 44(3):639649 Alsubaie N et al (2022) Statins use in Alzheimer disease: bane or boon from frantic search and narrative review

This is a tolerance response, not a medication problem, and nausea typically decreases over time