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GLP-1 receptor agonist use appeared linked to significantly reduced all-cause mortality among people with sickle cell disease, according to study results presented at ASH Annual Meeting and Exposition.People who used the medications also exhibited reduced risk for other adverse outcomes, including sickle cell crisis, venous thromboembolism, ischemic stroke or transient ischemic

However, combining medication with modest lifestyle changes typically yields better, longer-lasting results