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Benefits of Semaglutide GLP-1 for Medical Weight Loss Q&A Semaglutide is a weight-loss treatment that mimics the functions of GLP-1, a hormone that helps the body produce insulin and regulate blood sugar levels

GLP-1 (glucagon-like peptide-1) receptor agonists are a class of medications originally designed to help regulate blood sugar in people with type 2 diabetes

Exenatide (a GLP-1 agonist) expresses anti-inflammatory properties in cultured human monocytes/macrophages in a protein kinase A and B/Akt manner

Some plans approve GLP-1 medications at a starting BMI of 30 or higher, but require the BMI to remain at or above 30 to continue coverage