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As mentioned, tesofensine was originally developed as a prospective treatment for neurodegenerative diseases like Alzheimers and Parkinsons

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These impurities are then: Separated using high-resolution HPLC or UPLC Identified by accurate mass measurement via HRMS Structurally confirmed through amino acid sequencing by HRMS, NMR, or complementary techniques This process ensures that degradation products observed during long-term stability are already understood, characterized, and controlled