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It is approximately 44,000 times more selective for DPP-8 dpp-4 than DPP-8 and about 10,000 times more selective than DPP-9, which results in Linagliptin primarily targeting DPP-4 with very little effect on DPP-8 or DPP-9 [30]
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It examines both the therapeutic benefits and the safety considerations clinicians and patients must navigate, from common gastrointestinal side effects to rarer, more serious risks
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