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In another study , patients without T2D were more likely to stop using GLP-1 drugs: about 65% discontinued within a year, compared to 46% of those with type 2 diabetes

Semaglutide should be used cautiously for people on other blood sugar-lowering medications

The location of the pancreas

Because GLP-1 therapies delay gastric emptying, temporary discontinuation is recommended prior to procedures requiring anesthesia to reduce aspiration risk [32]
