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The good news is that regulators are taking actions to address these problems
Constructs that include the disulfide bond (I317C/G361C) are much sharper in curve transition compared to the control (no mutation, black line)
As the obesity drug pipeline expands from semaglutide and tirzepatide to triple agonists, oral formulations, and biased agonists, the side effect profiles are diverging in important ways
doi: 10.1038/s41386-019-0531-4
