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An alternative suggestion was that for patients with symptoms suggesting retained gastric contents, for whom delaying endoscopy may have negative clinical consequences, rapid-sequence intubation should be considered

Highlights from the ATTAIN-2 and ACHIEVE-3 trials demonstrate Orforglipron's significant therapeutic potential: Weight Reduction: In the ATTAIN-2 study (T2D & Obesity), the 36 mg dose achieved a -10.5% (-10.4 kg) body weight reduction at 52 weeks

PMID: 40044869 Cell Metab Gut enteroendocrine cell activation using a combination of GPR119 and GPR40 agonists results in synergistic hormone secretion in mice and humans

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