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Description
The first RCT to investigate the effect of liraglutide in patients with NAFLD was the LEAN study, in which 52 patients with NASH were randomized to either 48 weeks of treatment with liraglutide (1.8 mg/day) or placebo (66)

Constipation: Also common, sometimes alternating with diarrhea

Acts as an exercise mimetic due to its ability to enhance cardiorespiratory fitness and preserve muscle mass

Nature (2017) 549:4853
