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The American College of Gastroenterology (ACG) guidelines for the diagnosis and management of DGp state that a combination of appropriate symptoms and signs, along with delayed gastric emptying in the absence of gastric outlet obstruction or ulceration, is required to establish the diagnosis of DGp [4]

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Accelerating the titration schedule increases the risk of severe nausea, vomiting, and gastrointestinal distress without improving weight loss outcomes

A meta-analysis revealed that, compared with the GLP-1R agonists, placebo, and insulin, tirzepatide significantly reduced body mass index, waist circumference, and body weight [75]