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Here, we demonstrated that preferential accumulation of peroxidized phospholipids and loss of the antioxidant enzyme glutathione peroxidase 4 (GPX4) were responsible for vulnerability of midbrain dopaminergic neurons and progressive motor dysfunctions in a mouse model of PD

Pitx1 is a homeoprotein belonging to a class of transcription factors that are involved in organogenesis and cell differentiation

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