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Peripheral GLP-1/GLP-1RAs may also interact with the CNS indirectly by GLP-1R expressed on vagal afferent fibers, signaling via nodose ganglia (57) to the nucleus tractus solitarii within the brainstem

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More recent studies of isolated acini from mouse and rat pancreas showed a small but dose dependent stimulation of amylase release comparable to that induced by VIP or secretin (54, 98)
Benjamin Duffy, an Obesity Medicine Specialist at ThedaCare, emphasizes that a provider-guided tapering process typically takes about two months
